Biomedical Research Foundation of the Academy of Athens (BRFAA)
The Biobank at BRFAA offers and supports a large collection of state-of-the-art biobanking and sample analysis services. The facility provides biological samples (tissues, cells, fluids) accopmpanied by complete electronic clinical and socioeconomic data. The Biobank provides sample analysis by supporting sample handling, high throuput analysis of macromolecules (DNA, RNA and proteins), metabolites and data storage, curation and analysis. The facility also supports stem cell-based technologies for cell therapies.
The facility has a broad interest in translational research combining molecular biology, pharmacology, stem cell technologies and clinical research to study the molecular basis of diseases and develop the appropriate therapies. The team develops platforms and pipelines for the integration of biobanking, stem cell and systems biology, and large data management to achieve risk prediction, perform patient stratification and provide the clinicians with comprehensive information for better management and treatment of diseases like Parkinson’s Disease (PD), cardiovascular and immune-related diseases.
Technologies offered for the Open Call
- Biobanking services
a) Whole Genome Sequencing (30X)
b) Exome Sequencing (100X)
c) Data analysis
- Proteomics and Metabolomics
- Induced Pluripotent Stem Cells (iPSCs) production Platform
a) Biobanking of iPSCs
b) Differentiation schemes for iPSCs
d) Experimental cell therapy protocols
e) Transcriptomics-Proteomics-Metabolomics of differentiated cells
Additional resources offered for the Open Call
- Single cell genomics facility
- Mass cytometry (CyTof) system for single-cell proteome profiling
- Animal facility and experimental surgery facilities
- PET/CT for humans and PET/CT facility for small laboratory animals
- Clean Room (GMP facility) for stem cell-based therapies
Virtual and on-site. For virtual users, samples are processed for genomics, proteomics and stem cell-based asseays. On-site users perform their experiments supported by appropriate trained staff.
Scientific and technical requirements
The requested service should conform all bioethical regulations regarding anoymity of samples, consent forms, stem cell regulations and should be feasible.