CORBEL Catalogue of Services
Why do we need a Catalogue of Services?
Currently there are 13 biological and medical sciences Research Infrastructures (RIs) in Europe, all of them working jointly together in CORBEL towards offering shared services for life-science.
All RIs offer services, i.e. researchers from academia and industry can access their facilities, technologies and expertise. Services can simply be consultation, access to experts, but also access to data and biological samples, use of data analysis tools, access to facilities (e.g. highly specialised microscopes) plus support from technicians and much more.
The CORBEL Catalogue of Services is the first tool to list the main services of all these RIs at a glance and it aims to facilitate the utilisation of RI services by researchers from all over the world.
The Catalogue of Services as displayed below aims to provide you a basic overview on existing services within distinct thematic fields.
You can either use the Catalogue of Services to identify a single RI to help you with your work or you can create your own CORBEL service pipelines, i.e. using several RIs subsequently.
Examples of service pipelines are provided here.
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What’s your need?
Data & Databases
Technologies & Facilities
- accreditated/certified facilities (ISO certified, GLP, GMP, GCP)
- adaptation / development of assays (compounds etc.)
- adaptation / development of assays (human/non-human samples)
- high-throughput screening
- imaging (biological)
- imaging (medical)
- isolation / cultivation / characterisation of microorganisms
- -omics technology platforms
- plant phenotyping technologies/facilities
- production of high quality protein samples
- structural biology technologies/software
Models & Tools
Expertise & Support
- assessment of projects' impact and innovation potential
- biomarker validation
- biosecurity / biosafety (incl. regulatory) issues
- data management expertise
- development of project towards a medical application
- ethical / legal issues, informed consent
- mouse model generation, phenotyping and cryopreservation
- multinational clinical trial (establishment / management / monitoring)
- outbreak / emergency response / epidemiology
- support to submit a project proposal
- systems biology expertise
- training courses
- The following RIs offer complementary services:
Contact person(s): Anne-Charlotte Fauvel
EATRIS supports researchers in translating their findings into novel interventions including preventive, diagnostic or therapeutic products up to clinical proof of concept. The infrastructure comprises over 90 leading research institutions in the translational field located in 12 countries across Europe. EATRIS also supports the validation and development of novel (biological) tools for precision medicine and translational research in drug development. By providing access to accredited facilities as well as market-oriented expertise, including partnering, regulatory and health-technologuy assessment, your validation needs are covered in a one-stop shop.
Services offered by EATRIS include
- support funding applications (Identification of partners for consortium building, assessment of the project plan's impact and innovation potential)
- translational research facilities and expertise for development of novel biomarkers, diagnostics and therapeutics
- molecular, functional & hybrid imaging technologies, preclinical models, samples, patient cohorts, GMP manufacturing
- regulatory and Health Technology Assessment (HTA) expertise
- advice on intellectual property issues and industry partnering strategy
Why to work with us
EMPHASIS is a pan-European distributed plant phenotyping infrastructure project. EMPHASIS will focus on developing and enabling access to plant phenotyping infrastructure and provision of services, essential for the analysis of crop performance with respect to structure, function, quality and interaction with the environment. It will thus support the exploitation of crop genetic diversity required for the enhancement of plant productivity and progress in plant breeding.
In cooperation with EPPN2020, EMPHASIS offers access to plant phenotyping infrastructures, this includes
- high-throughput facilities
- lean field facilities
- intensive field facilities
- assay development
- data management
Further services are currently under development and will be implemented in its operational phase.
Why to work with us
EU-OPENSCREEN integrates high-capacity screening platforms throughout Europe, which jointly use a rationally selected compound collection, comprising up to 140.000 commercial and proprietary compounds collected from European chemists. EU-OPENSCREEN offers to researchers from academic institutions, SMEs and industrial organisations open access to its shared resources.
EU-OPENSCREEN will collaboratively develop novel molecular tool compounds with external users from various disciplines of the life sciences.
Services provided by EU-OPENSCREEN include
- high-throughput compound/ drug screening (HTS): HTS of an assay against the EU-OPENSCREEN chemical collection (> 100,000 compounds); in silico profiling; hit selection; confirmatory screening; basic counter screening; basic SAR based on screening data; QC of confirmed hits
- access to a unique European compound collection: EU-OPENSCREEN chemical collection (> 100,000 compounds)
- assay adaption: This assay adaptation process will involve a strong emphasis on quality, including: quality control of reagents; (patho-)physiological relevance; pharmacological consistency; robustness; minimised variability; and tracking of statistical descriptors
- chemical optimization and profiling of preliminary ‘hits’
- bioprofiling of donated compounds: All compounds donated by the user which enter the EU-OPENSCREEN ERIC compound collection are characterised and annotated for basic physico-chemical (e.g. identity, solubility, light absorbance and fluorescence) and essential to know biological properties (cytotoxicity, antibiotic, antifungal etc.) by testing in a standard panel of assays.
- provision of standardised data: All data generated through QC/bioprofiling and screening activities will be published in EU-OPENSCREEN’s open-access database with an optional ‘grace’ period (i.e. delayed publication of data). Large-scale open-access data provide the basis for computational data integration to obtain a systematic view, allow for prediction of drug-target interactions and networks as well as of adverse effects and drug combinations. The access to the EU-OPENSCREEN database will utilize the facilities of ChEMBL.
- training and education
Why to work with us
Contact person(s): Dr. Claudia Alen Amaro
Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to scientists. Access is provided free for academic scientists at Instruct centres and includes expert support.
Services offered by Instruct include
- structural analysis: Electron Microscopy (including CryoEM), Nuclear Magnetic Resonance (Solution and Solid State NMR), X-Ray crystallography Beamline;
- biophysical characterisation: Proteomic Mass Spectrometry, Surface Plasmon Resonance;
- sample preparation: Bacterial/Baculovirus/Mammalian/Yeast/Cell-Free expression, Nanobody Production, Crystallisation;
- data analysis: Image Processesing, Bioinformatics
Why to work with us
Contact person(s): MIRRI Interim Secretariat
MIRRI is the pan-European research infrastructure for microbial resources [i.e. bacteria (including cyanobacteria), archaea, fungi, yeasts, plant viruses, bacteriophages and their isolated DNA]. In addition, the MIRRI repertoire also covers human, animal and plant cell cultures.
By provision of high quality microorganisms, associated data and the broad expertise of our partners, MIRRI aims to support research and development in the field of biotechnology.
MIRRI services comprise
- access to microorganisms/cell lines deposited in public collections
- deposit of microorganisms/cell lines (public collection/patents)
- phenotypic/molecular characterisation of microorganisms
- identification/molecular typing of microorganisms
- isolation/cultivation/preservation of microorganisms
- microbial community analyses
- microbial phylogenetic studies
- screening/bioassays with microorganisms
- access to microbiological databases
- consultancy/contract research
- legal issues (e.g. Nagoya Protocol)
Why to work with us
Please note: Most of the RIs are constantly developing their portfolio of services, so if you do not find the service/tool you are looking for, do not hesitate to contact the RI and ask for it!